Roberto José Guerrero Isaza (born 16 November 1958, in Medellín) is a Colombian-American former racing driver. He participated in 29 Formula One Grands Prix, debuting on 23 January 1982.
With no championship points in Formula One and no prospects to drive for a competitive team, Guerrero left at the end of the 1983 season to race in the United States. He had an auspicious beginning to his Indycar racing career, winning both CART and Indianapolis 500 rookie of the year honors in 1984. His initial promise was never completely fulfilled, winning only two CART races, both in 1987. Later the same year he had a massive accident which left him in a coma for 17 days.
Of special note were Guerrero's participations in the Indianapolis 500. He came very close to winning outright on two occasions, but bad luck always kept the victory out of his grasp. In 1992 he spun off on the pace lap after having qualified on the pole position. Guerrero finished runner up twice, in the top-five five times, and held the qualifying speed record from 1992 through 1996.